How to Evaluate Microcirculation in Diabetics? |
Posted: October 17, 2019 |
Evaluating microcirculation in diabetics early on can help to develop a treatment plan that can help avoid complications like amputations. In the case of patient Rose D, early intervention helped save her great toe from amputation. Rose was a 63-year-old woman with a history of obesity, hypertension, high cholesterol, and severe diabetes with uncontrolled blood sugar levels. After suffering from an ingrown toenail, she later developed a large, deep, and bleeding ulcer on the tip of her left great toe. Analysis at a vascular surgery clinic clearly showed she was suffering from microcirculation malfunction due to her uncontrolled diabetes. Rose participated in a treatment regimen, consisting of strict blood sugar control and treatment with the transdermal vasodilator D’OXYVA, which effectively healed her ulcer and prevented amputation of her left great toe. What is Diabetes? Diabetes is a condition in which the pancreas is not able to produce the hormone insulin, which controls blood sugar levels, leading to abnormally high blood sugar levels. Elevated blood sugars can then cause damage to the large and small blood vessels supplying the eyes, feet, kidneys, heart, and nervous system, leading to end organ damage and organ failure. Symptoms of Diabetic Complications in the Feet Symptoms of diabetes mellitus-related foot complications include the following:
Avoiding Diabetic Foot Ulcers The risk of developing diabetic foot ulcers can be reduced by
How Does Diabetes Affect Microcirculation? Diabetes Company CA - Microcirculation refers to the very small blood vessels that branch off from larger blood vessels throughout the body to deliver oxygen and remove CO2 from the organs of the body. In diabetes, the chronically high blood sugar levels cause damage to the microcirculation1 through sclerosis (scarring) of the small blood vessel walls. This causes damage to both organs involved and the nerves supplying them. When the nerves are damaged in areas like the foot, there is a loss of what is known as protective sensation and a resultant failure to respond to normal pressures and irritations, thus leading to ulcers. Method 2 – Skin Pulp Blood Flow Skin pulp blood flow refers to the amount of blood flow in the pulp areas of the toes. This can be evaluated either by laser doppler fluxmetry, which measures the flow of red blood cells, or by comparing blood flows after administering a vasodilator (vasoreactivity). Summary Patients with severely reduced blood flow due to microcirculation damage from type 2 diabetes mellitus are at increased risk of developing complications such as painful foot ulcers. This is due to reduced blood flow and nerve damage, which prevent avoidance of undue friction and rubbing. Evaluating microcirculation dysfunction due to diabetes early in the course of the disease and treatment with modalities like D’OXYVA can help avoid complications like amputations. HOW D’OXYVA CAN HELP? Clinical studies with D’OXYVA (deoxyhemoglobin vasodilator) have shown* extraordinary results for the role of transdermal non-invasive wound care using ultra-purified, non-toxic FDA-cleared molecules, such as CO2, especially when all other approaches failed. In an ongoing multi-year, multi-country, multi-center, randomized clinical trial on patients with diabetic foot ulcers, D’OXYVA has demonstrated speeding up diabetic wound healing and ultimately wound closure to an average of 5 weeks.
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